0:00:11researcher michael sailor hopes that finding a low particles in this file the light up
0:00:16in the dark what they make treating cancer using your data on the cover
0:00:21first i got a lighter they got a glow a second as a gotta find
0:00:25that you
0:00:26i didn't reply of c and everything and that it is can see three girls
0:00:32what has been inari
0:00:34and three of us have to answer
0:00:37maggie and lydia both diagnosed and treated for breast cancer talk about the issues an
0:00:43image mine words you have cancer
0:00:47grammars effectively
0:00:49but they would like nothing the matter what kind of the enhanced what the one
0:00:55used to
0:00:55that is languishing for me to make a decision did you feel create a few
0:01:00tears
0:01:01a you have eight invited you feel the prior as you have it is not
0:01:07so
0:01:08and not show everything and everything twenty four seven
0:01:14at the university of california san diego sailors working to dramatically change those images a
0:01:21cancerous treated
0:01:22his request create at all particles that travel through the bloodstream latch on to cancers
0:01:28in their early stages and destroyed
0:01:31ideally you like to find the tumour when it's just one cell level a single
0:01:35cell of the cancerous tumour that's just starting to form
0:01:39we can do that now
0:01:41but one of the really long term goals of nanotechnology is to be able to
0:01:45do that
0:01:46whatsoever has done for the past twenty years is figure a way to make their
0:01:50low particles seek and destroy certain cancers in mice
0:01:54the end of stuff has been key for my research program
0:01:58because seventeen years ago received funding from the national science foundation c or wasn't thinking
0:02:04he has trying to figure out how to make an apart
0:02:09we didn't think about but in the body we just no well we can take
0:02:12visible silicon chips break them up and making and of particles adam
0:02:15what i silica
0:02:17because silicon can degrade in the body so far most byproducts so we really like
0:02:22to have an anal structure that once it gets into the body and does something
0:02:25then it goes away
0:02:27what's evolved is a recipe for making nontoxic narrow particles first take the silicon wafer
0:02:33same used to make computer chips and generate induced by using an electrochemical back
0:02:40punches tiny holes in the way for each ten thousand times smaller than the diameter
0:02:45of human here
0:02:47those holes are small but they're not so small that you can't loaded drug
0:02:51into those force what they are very small silicon sponges but the not that small
0:02:58there are still pretty big
0:02:59the next step is to turn the spongy waivers in the narrow particles
0:03:03so we have here is an ultrasonic bath
0:03:07basically a jury cleaner
0:03:09ultrasonic sound waves break up the silicon sponges and the smaller and smaller pieces
0:03:14these are quite you know structures these are still that microns scale we keep doing
0:03:19this process for valley hours these things would be small enough that we can inject
0:03:22them inside the body
0:03:23particles are also chemically coded to that of fluorescent well
0:03:29i want them to get into the body swim around inside the body find the
0:03:32tumour and then global and then allow us to be able to image
0:03:36today that all particles injected in mice are successfully helping researchers find certain cancers sailor
0:03:43hopes five to ten years as materials not be proved safe and effective for
0:03:50so that's one of the goals of nanotechnology you can build these vessels that can
0:03:54hold
0:03:55a drug that would normally be very toxic the body
0:03:59and in fact it's very toxic the tumour to
0:04:02and it holds that drive pizza from getting out until it finds the tumour and
0:04:06then it opens up and let's about
0:04:08what keeps it we're going but are zeros are dying every day and i get
0:04:14letters i'm dying cancer my wife assigning cancer my son design can see my nephew
0:04:19was dying of cancer can help us because but also i saw fixed point theorem
0:04:25steam
0:04:26future site is importance stress or having the personal interaction with the with a an
0:04:33old friend who who's you know husband died of cancer now on actually your mother
0:04:38in law has got cancer and now she's afraid that are daughters gonna have the
0:04:42same cancer "'cause" you know some generic can indication there
0:04:47you know
0:04:50you do you can do you can see survivor i really detection is fine
0:04:57unless anything have to remove that the sooner that they you know the timetables the
0:05:03better quality of life would you take the target
0:05:07since that answers the mis
0:05:12size nation and prosper