| 0:00:10 | my name is that it also for under the paper and sounds were growing risk |
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| 0:00:14 | importance agent called you site selection now trends and sign selection of the missing wrote |
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| 0:00:19 | one h two kinds of trial landscape between two thousand two thousand twelve it would |
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| 0:00:24 | just a dramatic increase in them on control facilities also known as sites |
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| 0:00:29 | the quality studies be more the key driving force behind this |
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| 0:00:32 | this is in a significant impact on the availability and selection what can control experience |
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| 0:00:37 | how can control inexperienced for naive signs |
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| 0:00:40 | given the perceived risks was selecting and that's very nice sites this study the recent |
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| 0:00:45 | trends inside selection and how we stress we managed is expansion into the global draw |
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| 0:00:50 | landscape using data collected from one hundred forty oncology trials with the number specific trends |
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| 0:00:56 | focusing on the number sign activated per year |
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| 0:00:59 | as expected that increased alongside locations stimulating right and the number of sites of rule |
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| 0:01:06 | however we also saw a significant decrease in the contribution of noisy sides to new |
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| 0:01:10 | study to than the region |
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| 0:01:12 | in fact but it into the user period this and twenty percent of all sides |
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| 0:01:16 | activated been classified as an i |
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| 0:01:20 | well this data highlights is that there is indeed a strong selection bias what experience |
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| 0:01:25 | signs of a nice size in the region the key reasons for the spice are |
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| 0:01:29 | likely to be the low recall rates all the start time lines i forty risks |
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| 0:01:33 | that are perceived to exist with these new science the current management strategy these additional |
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| 0:01:38 | risks |
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| 0:01:39 | appears to be reducing the number of no use only utilized to the absolute minimum |
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| 0:01:44 | which is mostly delivery be was entirely relied on previous the usual i size |
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| 0:01:50 | this raises the question of how also i one is yours expanding to increase the |
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| 0:01:54 | model and we are talking same sign over never again |
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| 0:01:58 | a critical point jump prosody only size maybe reach that will be necessary to reach |
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| 0:02:03 | out to additional new sites and grow disciple |
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| 0:02:07 | interestingly at that it shows that resulted experience slight bias |
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| 0:02:11 | this is not carry consistent that is that we see that has to some fluctuations |
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| 0:02:17 | so what is typically below the right part of what has it is reached a |
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| 0:02:21 | lot in certain outreach activities side is necessary to create a traditional trials |
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| 0:02:27 | clearly quality safety and performance i want to find his insight selection |
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| 0:02:32 | well with the current level of risk aversion unbiased what using the same troll size |
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| 0:02:36 | is not sustainable in a region experience level right present in asia |
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| 0:02:41 | in this i touching community we made a mindset change away from the current cycle |
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| 0:02:45 | of low risk or by some high risk |
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| 0:02:49 | a possibility would be to expand this i will be consistent inclusion of a number |
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| 0:02:53 | nine sites combined with correct training programs and of aside |
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| 0:02:57 | such a strategy would allow for the proper balance between eyesight risk an overall cycle |
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| 0:03:02 | graph |
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| 0:03:03 | i mean assuming that all ages a region of the next few years it'll be |
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| 0:03:07 | able to start piecing out actual terms at the concept of long term sustainability |
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