| 0:00:02 | no |
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| 0:00:08 | hello my name is my initial kind of each candidate cornell university biomedical engineering i |
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| 0:00:15 | work in laboratory a customisable king and that of our paper is which you're stress |
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| 0:00:21 | i can't yourself stress that really a services be tried there are set |
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| 0:00:27 | the motivation behind our work is to explore the treatment of circulating tumour cells to |
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| 0:00:33 | prevent an instrument task |
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| 0:00:35 | in basic terms may taxes occurs once cancer cells |
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| 0:00:40 | detached from primary tumour |
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| 0:00:41 | and enter the circulation |
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| 0:00:44 | e circulating tumour cells or c t c and utilized circulation is high |
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| 0:00:50 | and if you're within one that's able to travel into distinct issues and or secondary |
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| 0:00:55 | two hours |
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| 0:00:56 | for primary tumours |
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| 0:00:58 | surgery radiation there is generally successful in the tumour |
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| 0:01:03 | however once the test this occurs it is very challenging stops for cancer because very |
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| 0:01:09 | small tumours termite pasties |
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| 0:01:12 | more distinct issues under too small to detect and tree |
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| 0:01:17 | it is this mess that's right that a standard so that |
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| 0:01:21 | all that is currently exploring the idea of whether c d's can be treated in |
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| 0:01:26 | the luxury to reduce the channel estimate |
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| 0:01:30 | one there you take we are currently investigating straight |
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| 0:01:34 | which is unique in that induces so that in a variety of cancer so i |
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| 0:01:39 | s believes nearly all of a healthy cells on four |
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| 0:01:43 | trail one that receptors expressed on cancer cell service |
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| 0:01:47 | which can try arise in the presence of trail |
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| 0:01:50 | signal for programs so that notice a utterances |
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| 0:01:54 | one of the main differences between and result in the two remote requirement |
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| 0:01:59 | and the vascular my requirement |
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| 0:02:01 | if we which usually exposure |
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| 0:02:04 | with sheer force is much greater in the literature in that interpretation |
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| 0:02:09 | we were interested in addressing the question of whether exposure we would sure that how |
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| 0:02:14 | cancer cells respond there you section three |
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| 0:02:19 | the basis of our study was that we treated colin in prostate cancer cell trail |
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| 0:02:24 | and then expose the cancer cell which you're stress |
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| 0:02:28 | well we found was that we were fewer stress actually enhances the a i x |
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| 0:02:33 | trail when compared to sell that are suppose that conditions |
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| 0:02:38 | when we further increase the sheer force that cancer cell we're supposed to |
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| 0:02:43 | word increase the amount of time that cancer cells work suppose we will show forces |
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| 0:02:48 | percent variation in trails further |
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| 0:02:52 | what about other draws it's we which you're stressed and the duration of or that |
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| 0:02:57 | demonstrated by many kinds of problems |
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| 0:03:00 | to test this we also treated cell that's rooms |
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| 0:03:04 | and that using the treatment of cancer which induces cancer cells that using a different |
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| 0:03:10 | mechanism for training |
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| 0:03:11 | three along the surface was that there's the signal eight utterances where a person enters |
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| 0:03:17 | the cell and interpolated the unit which can a basic seller prosody and do so |
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| 0:03:24 | we discovered that we will shear stress had no measurable and that are sent induced |
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| 0:03:30 | errors |
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| 0:03:32 | whether solidworks suppose that conditions or due to stress but percentage of cell undergoing a |
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| 0:03:38 | services remain the same |
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| 0:03:41 | this indicates that and intonation patterns is specific to train three |
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| 0:03:47 | we also perform studies proving the molecular mechanism this sense the station |
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| 0:03:53 | when we definitely have had where within cancer cells which signals for trail and use |
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| 0:03:58 | eight utterances |
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| 0:04:00 | the entire a aren't responses at all |
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| 0:04:03 | indicating that the sense that the station it real task at hand so where assistance |
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| 0:04:08 | in addition to originate from |
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| 0:04:10 | we look for changes in the expression of receptors on serves of cancer cells |
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| 0:04:15 | what they're exposed if you stress or not |
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| 0:04:19 | the number that receptors on the self service remain unaltered |
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| 0:04:23 | future efforts will focus on examining which your trust best on the time position data |
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| 0:04:29 | centres as well as spatial distribution of that researchers on cancer cells |
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| 0:04:35 | the main conclusion of our study is that which you're stress exposure consent i can |
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| 0:04:41 | result to train three |
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| 0:04:43 | this can make trail an ideal candidate for the treatment of cancers task sizing the |
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| 0:04:49 | latch the future studies also reveal the possibility that receptors on c d c service |
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| 0:04:58 | which here |
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| 0:04:59 | we are currently investigating strategies to control how these receptors response which you're stress now |
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| 0:05:06 | or trail there |
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| 0:05:09 | this includes a video |
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| 0:05:11 | x y |
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