0:00:06hello my name is present only one pilot must i'm a sergeant and i'm currently
0:00:11collaborating with a reset the headed by doctors to feel more
0:00:15since fifteen years ago these thing is working on the relationship between the present of
0:00:19belfry not great deaf fixing plasma and cancer provision
0:00:23and in the present article we review the minus studies focus on the clinical utility
0:00:27assassin click that it's you know quality the present of a small amounts of the
0:00:32political click outfits impact mouse item name as synapse
0:00:36was firstly reported in the middle of twenty century
0:00:39however this phenomenon have a row set real interest in the scientific community only in
0:00:44the last three tickets
0:00:46in fact during those years it was verified that the amounts of regulating we caff
0:00:51it's a significant increase in cancer patients and they can carry a body of unity
0:00:56kind of between at the alterations related to cancer development operation differences you know this
0:01:01is referred to different times of that frame look like that it sets s
0:01:06dynamic meet the county a meter the in a and a renee and an eight
0:01:10and also micro letter name
0:01:12which presents in plasma has been recently reported
0:01:16how durations of those including because it's potentially reflect changes that occur during casinos carcinogen
0:01:22it is
0:01:23and include the ending with asian lost of itself because it the be that you
0:01:27know me consideration the eruption of micro every in a
0:01:31you permit elation of tumour suppressor genes and changes in the middle con the in
0:01:35a
0:01:36for this reason
0:01:37many studies have been i'm to find a clinical utility of the analyses of that
0:01:41fell free no because it's
0:01:43in the present article we have review the main findings related to the utility for
0:01:48every be analyses prominences and monitoring of a variety of cancer and although most of
0:01:53them have promising results
0:01:55the lack of harmonics asian of laboratory techniques the head of and heterogeneity of the
0:02:01disease progression and the small number of correctly but rectory depressions
0:02:05in the most of those of studies have resulting for translation of basically sets into
0:02:10clinical practice
0:02:11on the other hand blackman to play golf it's have that many ending about big
0:02:15aspects such as the release mechanisms of self prenuclear graph it's their biological function and
0:02:22the way by which this equality in the plot the stream
0:02:25probably the illustration of this is use might lead us to its end of the
0:02:30conception of that but the reality of concept
0:02:34theoretically
0:02:35self remotely caff it's would be a drop in the degraded in the bow the
0:02:38stream by nucleus as
0:02:40however dsc medication action maybe we need it because at least if part of substantively
0:02:47fast it's appear to be protected incorporate into complexes or particle
0:02:52whose a special characteristics might give protection against and thematic the relation
0:02:57the characterization of some particle of such particles pour complexes maybe a sense to clarify
0:03:03the origin of a class man apply caff it's
0:03:06many molecular pathways are probably involving starts a region
0:03:09seems a variety of reachable points in on the specific different directions
0:03:14it has been postulated that self reno click outfits regulating plasma i'm not many get
0:03:19as you got waste
0:03:20but such look like that it's might been directly involved in the development of met
0:03:24that's the sees through probably transactional about take myself that they will fit stuff the
0:03:29table cells
0:03:30ds theory name as the gentleman clusters is the only has been supported by us
0:03:35to wait a strong evidence namely the observation that plasma from constipation can't effect on
0:03:41court technically sound from cancer cells
0:03:44in conclusion
0:03:46although the original and the way of regulation of class method freaking because it's remain
0:03:50unclear
0:03:51there is a strong evidence that sets and because it's might become useful you're markers
0:03:56for a given will cease monitoring of cancer this is a moreover
0:04:00they might be essential into more development progression
0:04:03it is therefore expected that in the coming years and improve understanding of the relationship
0:04:08between synapse a molecular biology of concept we need to whether the illnesses management and
0:04:13the end of can so