| 0:00:00 | my name is wearing green my lab at johns hopkins is really interested in how |
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| 0:00:04 | we can develop new types of technologies to treat devastating brain cancers even with the |
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| 0:00:08 | best surgery chemotherapy radiation still is for patient outcomes |
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| 0:00:13 | we note developed a new technology it is a promise for treating the season anyway |
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| 0:00:19 | that is |
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| 0:00:28 | in the challenge with brain cancer answer |
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| 0:00:35 | it's a cancer cells where one supplied time normal self than a mutated increment control |
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| 0:00:40 | let's see we have the way back serious dominoes we can illustrate this concept |
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| 0:00:45 | so if we have some normal cells is it is a black dominoes here and |
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| 0:00:50 | cells are arranged |
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| 0:00:51 | next to each other and by their normal on their how people look at happens |
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| 0:00:55 | there could be mutations that |
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| 0:00:57 | heartedly genetic hardly be environmental |
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| 0:00:59 | where someone a change in cities |
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| 0:01:01 | cancer cells of different colours that are normal |
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| 0:01:05 | these cancer cells may also help this way potential you met their be words they |
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| 0:01:11 | can't really tell the difference between healthy sonic answers are really of ways and consonantal |
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| 0:01:15 | kill everything's of the cancer but there becomes the row so you know |
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| 0:01:19 | you're healthy cells and get your cancer cells this is why it's |
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| 0:01:23 | patients might lose their hair and i'm not at the end all these other complications |
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| 0:01:26 | and so what we like to do is to attack just doesn't answer self an |
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| 0:01:30 | average healthy so let's imagine the bees balloons yourself |
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| 0:01:34 | this will develop the technology to send instructions results to get into whatever we want |
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| 0:01:40 | this is a little bit like an electrical engineer to program a computer the biomedical |
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| 0:01:44 | engineer we wanna sell |
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| 0:01:46 | we actually wanna program |
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| 0:01:48 | cancer cells differently then helps |
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| 0:01:52 | this their mission impossible we were able to use as you technology to deliver instructions |
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| 0:01:57 | the cells to make them change a |
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| 0:01:59 | what color using the same type technology we can actually have the brain cancer cells |
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| 0:02:05 | of this process altogether |
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| 0:02:09 | this approach is called gene their the instructions the got the cancer cells to do |
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| 0:02:14 | what we wanted to those instructions come from the end up |
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| 0:02:17 | which is the a particle made of plastic in the in a and it's about |
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| 0:02:21 | a million times smaller than this particle here in indian is divided what it is |
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| 0:02:26 | it can safely deliver this cargo due to the different barriers |
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| 0:02:30 | and then like that information go to the right self starters |
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| 0:02:38 | we demonstrate this now |
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| 0:02:40 | in human brain cancer cells in a dish and in live mice in a really |
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| 0:02:44 | excited about the next steps as we move this forward to facial |
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| 0:02:48 | this type the discovery of possible here at hopkins do the natural collaborative atmosphere where |
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| 0:02:53 | myself the biomedical engineer i can work closely with excellent neurosurgeon them together |
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| 0:02:59 | as a team we can innovate these new technologies it can make an impact page |
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