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Video abstract of paper "Effect of melatonin on nocturnal blood pressure: meta-analysis of randomized controlled trials" published in the journal Vascular Health and Risk Management by Ehud Grossman, Moshe Laudon, Nava Zisapel. Read the perspectives article here: http://www.dovepress.com/effect-of-melatonin-on-nocturnal-blood-pressure-meta-analysis-of-rand-peer-reviewed-article-VHRM Conclusion: Add-on controlled-release melatonin to antihypertensive therapy is effective and safe in ameliorating nocturnal hypertension, whereas fast-release melatonin is ineffective. It is necessary that larger trials of longer duration be conducted in order to determine the long-term beneficial effects of controlled-release melatonin in patients with nocturnal hypertension.