my name is of course one and i prefer sort of buttons that might be
university
and then the end of the buttons and department and hypertension unit in the fine
she with the considered dimensional is one
and i'm working with melatonin for the last eight use of cleanliness not affect a
lot question before we start what does without the effects i would like to give
some in production model up we show i potential is one of the major risk
factors for called of a small
movement in modality and we know that not where shows some still could be an
pattern it usually goes down during the nighttime
and this pattern we call is called deep in butter
and in those patients so the laplacian l does not go down during the night
we talk about one db
and we know that these patients had higher cardiovascular voice
now we don't know why some variations out on the rails
but we know that one of the on one
that is responsible for falling asleep is reluctantly
but not only in is a more likely that was used by the united of
and that night
and it serves as the signal out for darkness in the organisation and the times
you for the biological clock
in the bright
no few years ago
wavefile that known deep as short less
off included in the log domain during nighttime this was probably used in lap ratio
eight years
seriously so that a lot on mean does not go up doing tonight i mean
on because we try to three
variations but not too not hypertension we reluctantly
and we well very successful
and showed
that but not only at night
can be can is
not to will not laplacian
this was published to all six
in the market module out of this
since then that well some additional studies
we not consistent results some stuff this confirms our observation that's melatonin can follow a
laplacian at night
but are does show no effect
therefore with the side the to collect all the information
available in the literature do a matter how does it is to show
what are the real effect of reluctantly
i will add darpa's was not only to see what is the effect but also
see that the is different effects of fast
and control willies reluctantly
if the onset of n
papers
including two hundred and twenty one patients
that well published
and when we define the that
studies and two dollars
we use faster is not only
and those labels controller
we'll have that
only control and is relatively
decrease significantly
and not to learn how do not show well as the fast lately and no
effect
so we believe that the addition of control but lately is will apply
two and t i intensive treatment
p l o l not to on the laplacian
if this is the case then this is mainly due significantly cardiovascular ability and modality