my name is that it also for under the paper and sounds were growing risk

importance agent called you site selection now trends and sign selection of the missing wrote

one h two kinds of trial landscape between two thousand two thousand twelve it would

just a dramatic increase in them on control facilities also known as sites

the quality studies be more the key driving force behind this

this is in a significant impact on the availability and selection what can control experience

how can control inexperienced for naive signs

given the perceived risks was selecting and that's very nice sites this study the recent

trends inside selection and how we stress we managed is expansion into the global draw

landscape using data collected from one hundred forty oncology trials with the number specific trends

focusing on the number sign activated per year

as expected that increased alongside locations stimulating right and the number of sites of rule

however we also saw a significant decrease in the contribution of noisy sides to new

study to than the region

in fact but it into the user period this and twenty percent of all sides

activated been classified as an i

well this data highlights is that there is indeed a strong selection bias what experience

signs of a nice size in the region the key reasons for the spice are

likely to be the low recall rates all the start time lines i forty risks

that are perceived to exist with these new science the current management strategy these additional

risks

appears to be reducing the number of no use only utilized to the absolute minimum

which is mostly delivery be was entirely relied on previous the usual i size

this raises the question of how also i one is yours expanding to increase the

model and we are talking same sign over never again

a critical point jump prosody only size maybe reach that will be necessary to reach

out to additional new sites and grow disciple

interestingly at that it shows that resulted experience slight bias

this is not carry consistent that is that we see that has to some fluctuations

so what is typically below the right part of what has it is reached a

lot in certain outreach activities side is necessary to create a traditional trials

clearly quality safety and performance i want to find his insight selection

well with the current level of risk aversion unbiased what using the same troll size

is not sustainable in a region experience level right present in asia

in this i touching community we made a mindset change away from the current cycle

of low risk or by some high risk

a possibility would be to expand this i will be consistent inclusion of a number

nine sites combined with correct training programs and of aside

such a strategy would allow for the proper balance between eyesight risk an overall cycle

graph

i mean assuming that all ages a region of the next few years it'll be

able to start piecing out actual terms at the concept of long term sustainability