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hello my name is my initial kind of each candidate cornell university biomedical engineering i
work in laboratory a customisable king and that of our paper is which you're stress
i can't yourself stress that really a services be tried there are set
the motivation behind our work is to explore the treatment of circulating tumour cells to
prevent an instrument task
in basic terms may taxes occurs once cancer cells
detached from primary tumour
and enter the circulation
e circulating tumour cells or c t c and utilized circulation is high
and if you're within one that's able to travel into distinct issues and or secondary
two hours
for primary tumours
surgery radiation there is generally successful in the tumour
however once the test this occurs it is very challenging stops for cancer because very
small tumours termite pasties
more distinct issues under too small to detect and tree
it is this mess that's right that a standard so that
all that is currently exploring the idea of whether c d's can be treated in
the luxury to reduce the channel estimate
one there you take we are currently investigating straight
which is unique in that induces so that in a variety of cancer so i
s believes nearly all of a healthy cells on four
trail one that receptors expressed on cancer cell service
which can try arise in the presence of trail
signal for programs so that notice a utterances
one of the main differences between and result in the two remote requirement
and the vascular my requirement
if we which usually exposure
with sheer force is much greater in the literature in that interpretation
we were interested in addressing the question of whether exposure we would sure that how
cancer cells respond there you section three
the basis of our study was that we treated colin in prostate cancer cell trail
and then expose the cancer cell which you're stress
well we found was that we were fewer stress actually enhances the a i x
trail when compared to sell that are suppose that conditions
when we further increase the sheer force that cancer cell we're supposed to
word increase the amount of time that cancer cells work suppose we will show forces
percent variation in trails further
what about other draws it's we which you're stressed and the duration of or that
demonstrated by many kinds of problems
to test this we also treated cell that's rooms
and that using the treatment of cancer which induces cancer cells that using a different
mechanism for training
three along the surface was that there's the signal eight utterances where a person enters
the cell and interpolated the unit which can a basic seller prosody and do so
we discovered that we will shear stress had no measurable and that are sent induced
errors
whether solidworks suppose that conditions or due to stress but percentage of cell undergoing a
services remain the same
this indicates that and intonation patterns is specific to train three
we also perform studies proving the molecular mechanism this sense the station
when we definitely have had where within cancer cells which signals for trail and use
eight utterances
the entire a aren't responses at all
indicating that the sense that the station it real task at hand so where assistance
in addition to originate from
we look for changes in the expression of receptors on serves of cancer cells
what they're exposed if you stress or not
the number that receptors on the self service remain unaltered
future efforts will focus on examining which your trust best on the time position data
centres as well as spatial distribution of that researchers on cancer cells
the main conclusion of our study is that which you're stress exposure consent i can
result to train three
this can make trail an ideal candidate for the treatment of cancers task sizing the
latch the future studies also reveal the possibility that receptors on c d c service
which here
we are currently investigating strategies to control how these receptors response which you're stress now
or trail there
this includes a video
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