my name is wearing green my lab at johns hopkins is really interested in how
we can develop new types of technologies to treat devastating brain cancers even with the
best surgery chemotherapy radiation still is for patient outcomes
we note developed a new technology it is a promise for treating the season anyway
that is
in the challenge with brain cancer answer
it's a cancer cells where one supplied time normal self than a mutated increment control
let's see we have the way back serious dominoes we can illustrate this concept
so if we have some normal cells is it is a black dominoes here and
cells are arranged
next to each other and by their normal on their how people look at happens
there could be mutations that
heartedly genetic hardly be environmental
where someone a change in cities
cancer cells of different colours that are normal
these cancer cells may also help this way potential you met their be words they
can't really tell the difference between healthy sonic answers are really of ways and consonantal
kill everything's of the cancer but there becomes the row so you know
you're healthy cells and get your cancer cells this is why it's
patients might lose their hair and i'm not at the end all these other complications
and so what we like to do is to attack just doesn't answer self an
average healthy so let's imagine the bees balloons yourself
this will develop the technology to send instructions results to get into whatever we want
this is a little bit like an electrical engineer to program a computer the biomedical
engineer we wanna sell
we actually wanna program
cancer cells differently then helps
this their mission impossible we were able to use as you technology to deliver instructions
the cells to make them change a
what color using the same type technology we can actually have the brain cancer cells
of this process altogether
this approach is called gene their the instructions the got the cancer cells to do
what we wanted to those instructions come from the end up
which is the a particle made of plastic in the in a and it's about
a million times smaller than this particle here in indian is divided what it is
it can safely deliver this cargo due to the different barriers
and then like that information go to the right self starters
we demonstrate this now
in human brain cancer cells in a dish and in live mice in a really
excited about the next steps as we move this forward to facial
this type the discovery of possible here at hopkins do the natural collaborative atmosphere where
myself the biomedical engineer i can work closely with excellent neurosurgeon them together
as a team we can innovate these new technologies it can make an impact page